Statistics of Primera División Uruguaya in season 1916.
It was contested by 9 teams, and Nacional won the championship.
| Pos | Club | P | W | D | L | GF | GA | Pts |
| 1 | Nacional | 16 | 14 | 2 | 0 | 28 | 5 | 30 |
| 2 | Peñarol | 16 | 7 | 4 | 5 | 29 | 19 | 18 |
| 3 | Montevideo Wanderers | 16 | 7 | 3 | 6 | 13 | 20 | 17 |
| 4 | Central | 16 | 6 | 3 | 7 | 16 | 17 | 15 |
| 5 | River Plate | 16 | 4 | 5 | 7 | 18 | 17 | 13 |
| 6 | Universal | 16 | 3 | 7 | 6 | 16 | 19 | 13 |
| 7 | Dublin | 16 | 4 | 5 | 7 | 13 | 17 | 13 |
| 8 | Defensor | 16 | 4 | 5 | 7 | 10 | 17 | 13 |
| 9 | Reformers | 16 | 5 | 2 | 9 | 10 | 22 | 12 |
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